A QCM-VNA System for Microfluidic Sensing: Leveraging Higher-Order Harmonics

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dc.contributor.authorKoltuk, Eren
dc.contributor.authorDemir, Saibe
dc.contributor.authorYalcin, Eren
dc.contributor.authorDemir, Kerim Alaz
dc.contributor.authorKahveci, Ebrar
dc.contributor.authorBatur, Okan Zafer
dc.contributor.authorKirimli, Ceyhun Ekrem
dc.date.accessioned2026-04-04T18:55:51Z
dc.date.available2026-04-04T18:55:51Z
dc.date.issued2025
dc.departmentİstanbul Bilgi Üniversitesi
dc.description21st International Conference on Synthesis, Modeling, Analysis and Simulation Methods and Applications to Circuit Design-SMACD -- JUL 07-10, 2025 -- Istanbul, TURKIYE
dc.description.abstractThis paper presents the design and development of a QCM-based VNA measurement system capable of detecting magnitude and phase responses of higher-order harmonics with a 19-Hz resolution. A fast-locking algorithm is implemented to efficiently track changes in the QCM response within a microfluidic channel. The S11 reflection measurements obtained from the VNA are used to extract the magnitude and phase characteristics of the QCM. Measurements were performed at the fifth harmonic (50 MHz) of the quartz crystal. The QCM response can be detected in 12 seconds for 500 data points using the fast sweep and locking algorithm. The measurement results are taken on glycerol in 2%, 5%, and 10% (v/v) concentrations. Limit of detection (LOD) was calculated as 2% glycerol. The baseline stability of the 5th overtone resonance peak in deionized water was calculated approximate to at 35 Hz.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [122E166]
dc.description.sponsorshipThis work was supported by The Scientific and Technological Research Council of Turkey (TUBITAK) under Contract 122E166
dc.description.sponsorshipInstitute of Electrical and Electronics Engineers Inc
dc.identifier.doi10.1109/SMACD65553.2025.11091915
dc.identifier.doi10.1109/SMACD65553.2025.11091915
dc.identifier.isbn979-8-3315-2396-1
dc.identifier.isbn979-8-3315-2395-4
dc.identifier.issn2575-4874
dc.identifier.issn2575-4890
dc.identifier.scopus2-s2.0-105013463132
dc.identifier.scopusqualityN/A
dc.identifier.urihttps://doi.org/10.1109/SMACD65553.2025.11091915
dc.identifier.urihttps://hdl.handle.net/11411/10592
dc.identifier.wosWOS:001554977800007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherIeee
dc.relation.ispartof2025 21St International Conference on Synthesis, Modeling, Analysis and Simulation Methods, and Applications to Circuits Design, Smacd
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_WoS_20260402
dc.snmzKA_Scopus_20260402
dc.subjectVna
dc.subjectReflectometer
dc.subjectMicrofluidics
dc.subjectQcm
dc.subjectSensors
dc.titleA QCM-VNA System for Microfluidic Sensing: Leveraging Higher-Order Harmonics
dc.typeConference Object

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