Quantitative detection system for immunostrips in 180nm standard CMOS technology

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dc.authoridSarioglu, Baykal/0000-0002-7433-3823
dc.authorwosidGul, Ozgur/A-7841-2011
dc.contributor.authorTekin, Engincan
dc.contributor.authorCelikdemir, Caner
dc.contributor.authorUcar, Busra
dc.contributor.authorGul, Ozgur
dc.contributor.authorSarioglu, Baykal
dc.date.accessioned2024-07-18T20:40:38Z
dc.date.available2024-07-18T20:40:38Z
dc.date.issued2021
dc.departmentİstanbul Bilgi Üniversitesien_US
dc.description.abstractIn this work, a CMOS based optical read-out system for biomarker on immunostrips detection is presented. For the proposed system, a CMOS integrated circuit containing an on-chip photodiode is designed in standard 180 nm UMC CMOS Technology. The system also contains cost-effective 3D Printed structures for holding both IC and the sample immunostrip together. The proposed system can be operated in two modes (1) light reflectance and (2) light transmittance. In the system, a laser with a wavelength of 637 nm is applied to the CMOS IC through immunostrip. Photovoltaic and photoconductive measurements are carried out for each mode on a custom Gluten biomarker immunostrip. Sensing operation of the biomarker is successfully realized with optical powers from 5 mW to 8 mW. Biomaterial density on the immunostrip is sensed and images of the biomarker with varying intensities are constructed from the measurements. Feasibility of the system for low power biomarker sensing applications is demonstrated.en_US
dc.identifier.doi10.1007/s10470-020-01712-y
dc.identifier.endpage500en_US
dc.identifier.issn0925-1030
dc.identifier.issn1573-1979
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85091147728en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage493en_US
dc.identifier.urihttps://doi.org/10.1007/s10470-020-01712-y
dc.identifier.urihttps://hdl.handle.net/11411/7153
dc.identifier.volume106en_US
dc.identifier.wosWOS:000571381700001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAnalog Integrated Circuits and Signal Processingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiosensingen_US
dc.subjectCmosen_US
dc.subjectOptical Sensoren_US
dc.subjectBiomarkeren_US
dc.subjectOptical Receiveren_US
dc.subjectImmunosensoren_US
dc.titleQuantitative detection system for immunostrips in 180nm standard CMOS technology
dc.typeArticle

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